POTENSI INTERAKSI OBAT AMLODIPIN PADA PASIEN HIPERTENSI DISALAH SATU PUSKESMAS KABUPATEN SUMEDANG

Authors

  • Ani Anggriani Sekolah Tinggi Farmasi Bandung
  • Eva Kusumahati Universitas Bhakti Kencana Bandung
  • Irfan Hilmi Mutazam Universitas Bhakti Kencana Bandung

DOI:

https://doi.org/10.33759/jrki.v3i1.108

Keywords:

Interaksi Obat, Hipertensi, Amlodipin

Abstract

Hypertension is still a main health problem in indonesia, the purpose of this research is to know the profile of the antihypertensive agent and the interaction potency of the drugs and the relation between the amount of the drugs towards the interaction occurrence in public health centre of sukasari in district of sumedang by the period of July-December 2019. This was observational research with descriptive method. The data collection was performed using drug interaction checker software. There are data of 112 patients. The analysis was performed quantitatively and qualitatively. the result shows the interaction occurrence are happened to woman with percentage of 90% in age group of 65-74 years (30%). Hypertension stage 2 is the most occurred (69%), also there are 82 (73%) patients with potentially might have interaction, meanwhile from all medicines, there are 116 occurrence of interatction might happen. The most interaction occurred happen to amlodipin and hycrochlorothiazide (41%), with pharmacodynamic interaction of 62% and minor severity of 62%.

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References

Faturrahman, M. (2013). Analisis Potensi Interaksi Obat dan Manifestasi Klinik Resep Anak di Apotek Bandung Analysis of Potential Drug-Drug Interactions and Its Clinical Manifestation of Pediatric Prescription on 2 Pharmacies in Bandung. Jurnal Farmasi Klinik Indonesia, 2(3), 121–126.

Baxter, K. (2006). Stockley’s Drug Interactions, 8th Edition. Annalsof Pharmacotherapy, 40(6), 1219–1219. https://doi.org/10.1345/aph.1g691

Baxter, K. (2010). Stockley’s drug interactions: a source book of interactions, their mechanisms, clinical importance and management. Choice Reviews Online, 48(03), 48-1222-48– 1222. https://doi.org/10.5860/choice.48-1222

Diii, P., & Lubuklinggau, K. (2012). ANALISIS FAKTOR RISIKO PENYAKIT HIPERTENSI PADA MASYARAKAT DI KECAMATAN KEMUNING KOTA PALEMBANG TAHUN 2012 RISK FACTORS ANALYZE OF HYPERTENSION ON COMMUNITY AT KEMUNING SUB DISTRICTIN PALEMBANG 2012 hipertensi di Indonesia cukup tinggi , yaitu 8,3 % per. 1(10), 170–178.

Joint, G., & Committee, N. (2016). JNC 8: Evidence-based Guideline Penanganan Pasien Hipertensi Dewasa. 43(1), 54–59.

Kandarini, Y. (2017). Tatalaksana Farmakologi Terapi Hipertensi. Divisi Ginjal Dan Hipertensi RSUP Sanglah Denpasar.

Kemenkes.RI. (2014). Pusdatin Hipertensi. Infodatin, (Hipertensi), 1– 7. https://doi.org/10.1177/109019817400200403
Kemenkes.RI, & Arianie, P. (2019). Hipertensi penyakit paling banyak diidap masyarakat. 2017–2020.

Krause, T., Lovibond, K., Caulfield, M., McCormack, T., & Williams, B. (2011). Management of hypertension: Summary of NICE guidance. BMJ (Online), 343(7821). https://doi.org/10.1136/bmj.d4891

Mancia, G., Fagard, R., Narkiewicz, K., Redon, J., Zanchetti, A., Böhm, M., … Wood, D. A. (2013). 2013 ESH/ESC guidelines for the management of arterial hypertension: The Task Force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). European Heart Journal, 34(28), 2159– 2219. https://doi.org/10.1093/eurheartj/eht151

Pamu, S., Singh, T., Ravi, S., & Ranganayakulu, S. V. (2017). Evaluations of Drug-Drug Interactions in Hypertensive Patients in Secondary Care Hospital. IOSR Journal of Pharmacy and Biological Sciences, 12(02), 45–50. https://doi.org/10.9790/3008-1202044550

Radjamuda, N., & Montolalu, A. (2014). Faktor-Faktor Risiko Yang Berhubungan Dengan Kejadian Hipertensi Pada Ibu Hamil Di Poli Klinik Obs-Gin Rumah Sakit Jiwa Prof. Dr. V. L. Ratumbuysang Kota Manado. Jurnal Ilmiah Bidan, 2(1), 91509.

Riskesdas, 2018. (2018). HASIL UTAMA RISKESDAS 2018.

Salfitri, Nurmainah, & Yuswar, M. A. (2017). Kajian Interaksi Obat Antihipertensi pada Pasien Hemodialisis Di Rumah Sakit Umum Yarsi Pontianak Tahun 2017.

Tandililing, S., Mukaddas, A., & Faustine, I. (2017). Profil Penggunaan Obat Pasien Hipertensi Esensial di Instalasi Rawat Jalan Rumah Sakit Umum Daerah I Lagaligo Kabupaten Luwu Timur Periode Januari-Desember Tahun 2014. GALENIKA Journal of Pharmacy, 3(1), 49–56.

Tarigan, A. R., Lubis, Z., & Syarifah, S. (2018). Pengaruh Pengetahuan, Sikap Dan Dukungan Keluarga Terhadap Diet Hipertensi Di Desa Hulu Kecamatan Pancur Batu Tahun 2016. Jurnal Kesehatan, 11(1), 9–17. https://doi.org/10.24252/kesehatan.v11i1.5107

White, W. B. (2009). Defining the Problem of Treating the Patient with Hypertension and Arthritis Pain. American Journal of Medicine, 122(5 SUPPL.), S3–S9. https://doi.org/10.1016/j.amjmed.2009.03.002

Widjaya, N., Anwar, F., Laura Sabrina, R., Rizki Puspadewi, R., & Wijayanti, E. (2019). Hubungan Usia Dengan Kejadian Hipertensi di Kecamatan Kresek dan Tegal Angus, Kabupaten Tangerang. YARSI Medical Journal, 26(3), 131. https://doi.org/10.33476/jky.v26i3.756

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Published

2021-01-05

How to Cite

POTENSI INTERAKSI OBAT AMLODIPIN PADA PASIEN HIPERTENSI DISALAH SATU PUSKESMAS KABUPATEN SUMEDANG. (2021). Jurnal Riset Kefarmasian Indonesia, 3(1), 1-9. https://doi.org/10.33759/jrki.v3i1.108