PENETAPAN KADAR FLAVONOID TOTAL EKSTRAK DAUN Litsea elliptica Blume

Authors

  • Pra Panca Bayu Chandra Sekolah Tinggi Ilmu Kesehatan IKIFA
  • Indri Astuti Handayani Program Studi Farmasi, Sekolah Tinggi Ilmu Kesehatan IKIFA

DOI:

https://doi.org/10.33759/jrki.v6i2.513

Keywords:

Ekstrak Daun Litsea elliptica, Kadar Flavonoid Total, Metode Kolorimetri-Aluminium Klorida, Spektrofotometri UV-Vis

Abstract

Kalimantan Island is an area with forests that can be developed for potential results, especially in plants with medicinal properties for health. The medicinal properties of plants are the role of the secondary metabolites contained in them. One of them is Litsea, a plant that comes from the Lauraceae family with 45 genera and more than 2,000 species. Plants from this genus are widely used by the community as traditional medicine, especially Litsea elliptica. One of the secondary metabolite contents of Litsea elliptica is flavonoids. The aim of this research was to determine the flavonoid content of Litsea elliptica leaf extract. The extraction process was carried out by maceration with 96% ethanol solvent. The results of the maceration extraction are then carried out by evaporation until a thick extract is obtained. The total flavonoid content was determined using the Colorimetric-Aluminum Chloride Method with a UV-Vis spectrophotometric instrument, resulting in a total flavonoid content of Litsea elliptica leaf extract of 391.01 mg ± 0.27 mg. The conclusion of this research is that Litsea elliptica leaf extract has a flavonoid content of 0.39%

Downloads

Download data is not yet available.

References

Alfaridz, F., & Amalia, R. (2019). Review Jurnal : Klasifikasi Dan Aktivitas Farmakologi Dari Senyawa Aktif Flavonoid. Farmaka, 3, 1–9.

Aminah, A., Tomayahu, N., & Abidin, Z. (2017). Penetapan Kadar Flavonoid Total Ekstrak Etanol Kulit Buah Alpukat (Persea americana Mill.) Dengan Metode Spektrofotometri UV-VIS. Jurnal Fitofarmaka Indonesia, 4(2), 226–230. https://doi.org/10.33096/jffi.v4i2.265

Anjani, P. P. (2018). Potensi Antidiabetes Ekstrak Okra Ungu (Abelmoschus esculentus L.) pada Tikus Model Diabetes yang Diinduksi Streptozotocin. Journal of Bogor Agricultural Instittute, 1(2), 2018.

Azizah, D. N., Kumolowati, E., & Faramayuda, F. (2014). Penetapan Kadar Flavonoid Metode Aluminium Klorida pada Ekstrak Metanol Kulit Buah Kakao (Theobroma cacao L.). Kartika Jurnal Ilmiah Farmasi, 2(2), 45–49. https://doi.org/10.26874/kjif.v2i2.14

Chandra, P. P. B., Laksmitawati, D. R., & Rahmat, D. (2022). Skrining Fitokimia Dan Penetapan Kadar Flavonoid Total Ekstrak Buah Okra (Abelmoschus esculentus L.). Jurnal Kefarmasian Akfarindo, 7(2), 29–36. https://doi.org/10.37089/jofar.vi0.149

Fathurrahman, N. R., & Musfiroh, I. (2018). Artikel Tinjauan: Teknik Analisis Instrumentasi Senyawa Tanin. Farmaka, 4(2), 449–456.

Goh, M. P. Y., Basri, A. M., Yasin, H., Taha, H., & Ahmad, N. (2017). Ethnobotanical review and pharmacological properties of selected medicinal plants in Brunei Darussalam: Litsea elliptica, Dillenia suffruticosa, Dillenia excelsa, Aidia racemosa, Vitex pinnata and Senna alata. Asian Pacific Journal of Tropical Biomedicine, 7(2), 173–180. https://doi.org/10.1016/j.apjtb.2016.11.026

Handayani, I. A., Panca, P., & Chandra, B. (2024). Skrining Fitokimia dan Penetapan Kadar Tanin Ekstrak Daun Litsea elliptica Blume. Jurnal Ilmu Kefarmasian, No ……(1), 53–60.

Hermawati, E., Panca, P., Chandra, B., Christian, Y. E., Farmasi, P. S., Matematika, F., & Alam, P. (2023). STANDARISASI SIMPLISIA DAN PENETAPAN KADAR FLAVONOID PADA EKSTRAK ETANOL 96 % BUAH OKRA MERAH DAN HIJAU ( Abelmoschus esculentus ( L .) Moench ). 8(2), 138–146.

Julianto, T. S. (2019). Fitokimia Tinjauan Metabolit Sekunder dan Skrining fitokimia. In Jakarta penerbit buku kedokteran EGC (Vol. 53, Issue 9).

Kamle, M., Mahato, D. K., Lee, K. E., Bajpai, V. K., Gajurel, P. R., Gu, K. S., & Kumar, P. (2019). Ethnopharmacological properties and medicinal uses of litsea cubeba. Plants, 8(6), 1–13. https://doi.org/10.3390/plants8060150

Kazmi, A., Khan, M. A., & Ali, H. (2019). Biotechnological approaches for production of bioactive secondary metabolites in Nigella sativa:¬ an up-to-date review. International Journal of Secondary Metabolite, 6(2), 172–195. https://doi.org/10.21448/ijsm.575075

Kusparadini, H., Putri, A. S., & Diana, R. (2018). Potensi Tumbuhan Genus Litsea.

Kuspradini, H., Sinta, S. S., & Putri, A. S. (2021). Karakteristik Minyak Atsiri dari Tumbuhan Aromatik Hutan Tropis Jenis Litsea spp dan Potensinya sebagai Antimikroba. Minyak Atsiri: Produksi Dan Aplikasinya Untuk Kesehatan, 50–84.

Lisnawati, N., Handayani, I. A., & Fajrianti, N. (2016). Analisa flavonoid dari ekstrak etanol 96% kulit buah okra merah (Abelmoschus esculentus L. Moench) secara kromatografi lapis tipis dan spektrofotometri UV-VIS. Ilmiah Ibnu Sina, 1(1), 105–112.

Malangngi, L., Sangi, M., & Paendong, J. (2012). Penentuan Kandungan Tanin dan Uji Aktivitas Antioksidan Ekstrak Biji Buah Alpukat (Persea americana Mill.). Jurnal MIPA, 1(1), 5. https://doi.org/10.35799/jm.1.1.2012.423

Nofita, D., Sari, S. N., & Mardiah, H. (2020). Penentuan Fenolik Total dan Flavonoid Ekstrak Etanol Kulit Batang Matoa (Pometia pinnata J.R& G.Forst) secara Spektrofotometri. Chimica et Natura Acta, 8(1), 36. https://doi.org/10.24198/cna.v8.n1.26600

Parwata, I. M. O. (2016). Kimia Organik Bahan Alam Flavanoid. Diktat Bahan Ajar Universitas Udayana, 1–51.

Putri, Y. A., Muharini, R., Lestari, I., Masriani, M., Rudiyansyah, R., & Ola, A. R. B. (2024). Profil Kandungan Kimia, Fenolik Total, dan Aktivitas Antioksidan Ekstrak Etanol Tumbuhan Litsea firma (Blume) Hook F. ALCHEMY Jurnal Penelitian Kimia, 20(1), 38. https://doi.org/10.20961/alchemy.20.1.74158.38-48

Rabiatul Adawiyah, Siti Maimunah, & Pienyani Rosawanti. (2019). Keanekaragaman Tumbuhan Potensi Obat Tradisional di Hutan Kerangas Pasir Putih KHDTK UM Palangkaraya. Talenta Conference Series: Agricultural and Natural Resources (ANR), 2(1), 71–79. https://doi.org/10.32734/anr.v2i1.576

Suksamerkun, W., Thongsomchitt, S., Wongkrajang, Y., Temsiririrkkul, R., Kitphati, W., & Thongpraditchote, S. (2013). Screening of antioxidant activity of vegetables in Thailand. Journal of Asian Association of Schools of Pharmacy, 2, 254–261. http://www.aaspjournal.org/abstractinfo.php?id=52

Susila Ningsih, I., Chatri, M., & Advinda, L. (2023). Flavonoid Active Compounds Found In Plants Senyawa Aktif Flavonoid yang Terdapat Pada Tumbuhan. Serambi Biologi, 8(2), 126–132.

Tamin, R. P., Ulfa, M., & Saleh, Z. (2018). Keanekaragman Anggota Famili Lauraceae di Taman Hutan Kota M Sabki Kota Jambi. Journal of LPPM Jambi University, 2(2), 128–134.

Werdiningsih, W., Tia Pratiwi, N., & Yuliati Institut Ilmu Kesehatan Bhakti Wiyata Kediri, N. (2022). PENETAPAN KADAR FLAVONOID EKSTRAK ETANOL 70% DAUN BINAHONG (Anredera cordifolia [Ten] Steenis) DI DESA PELEM, TANJUNGANOM, KAB. NGANJUK Determination Of 70% Ethanol Extract Flavonoid Total Levels Binahong (Anredera Cordifolia [Ten] Steenis) Leaves In Pele. J. Sintesis Submitted: 12 Desember, 2022(2), 54–61.

Wong, M. H., Lim, L. F., Ahmad, F. bin, & Assim, Z. bin. (2014). Antioxidant and antimicrobial properties of Litsea elliptica Blume and Litsea resinosa Blume (Lauraceae). Asian Pacific Journal of Tropical Biomedicine, 4(5), 386–392. https://doi.org/10.12980/APJTB.4.2014C1129

Downloads

Published

2024-05-29

How to Cite

PENETAPAN KADAR FLAVONOID TOTAL EKSTRAK DAUN Litsea elliptica Blume. (2024). Jurnal Riset Kefarmasian Indonesia, 6(2), 192-206. https://doi.org/10.33759/jrki.v6i2.513